Parkinson's disease is a progressive neurological condition of the central nervous system that mainly affects the motor system. As the disease worsens, non-motor symptoms become increasingly common such as difficulty sleeping. People with Parkinson's don't have enough of the chemical dopamine because some of the nerve cells that make it have died. Parkinson’s develops when cells in the brain stop working properly and are lost over time. These brain cells produce a chemical called dopamine. Symptoms start to appear when the brain can’t make enough dopamine to control movement properly.
The number of people diagnosed with Parkinson's in the UK is about 145,000. That's around 1 adult in every 350.
The symptoms generally come on slowly over time. Early in the disease, the most obvious are shaking, rigidity, slowness of movement, and difficulty with walking. Thinking and behavioural problems may also occur. Dementia becomes common in the advanced stages of the disease.
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